104 research outputs found

    Better Nature by Fenn Stewart

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    Review of Fenn Stewart\u27s Better Nature

    Field Notes for the Alpine Tundra by Elena Johnson

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    Review of Elena Johnson\u27s poetry collection, Field Notes for the Alpine Tundra

    Feasibility Evaluation of Radioimmunoguided Surgery of Breast Cancer

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    Breast-conserving surgery involves completely excising the tumour while limiting the amount of normal tissue removed, which is technically challenging to achieve, especially given the limited intraoperative guidance available to the surgeon. This study evaluates the feasibility of radioimmunoguided surgery (RIGS) to guide the detection and delineation of tumours intraoperatively. The 3D point-response function of a commercial gamma-ray-detecting probe (GDP) was determined as a function of radionuclide (131I, 111In, 99mTc), energy-window threshold, and collimator length (0.0–3.0-cm). This function was used to calculate the minimum detectable tumour volumes (MDTVs) and the minimum tumour-to-background activity concentration ratio (T:B) for effective delineation of a breast tumour model. The GDP had larger MDTVs and a higher minimum required T:B for tumour delineation with 131I than with 111In or 99mTc. It was shown that for 111In there was a benefit to using a collimator length of 0.5-cm. For the model used, the minimum required T:B required for effective tumour delineation was 5.2 ± 0.4. RIGS has the potential to significantly improve the accuracy of breast-conserving surgery; however, before these benefits can be realized, novel radiopharmaceuticals need to be developed that have a higher specificity for cancerous tissue in vivo than what is currently available

    Teaching on insecure foundations? Pre-service teachers in England’s perceptions of the wider curriculum subjects in primary schools

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    Subject marginalisation is an on-going concern across the primary education sector, particularly for the arts and humanities. This poses issues for pre-service teacher partnerships and for higher education institutions (HEIs) evaluating the role of subjects within their teacher training courses as they reform their curricula to prepare students to teach across diverse educational contexts. Through the interpretation of student voice, we disseminate a case study with primary initial teacher education (ITE) students that investigates learner perceptions of their training in under-represented foundation subjects. Emerging themes include tensions between university and school-based practices, and between curriculum models, together with the need to develop student adaptability and self-direction. The authors propose that if ITE students explore and take on the dispositions of changemakers, they will become equipped with the self-efficacy and adaptability needed to develop secure bases for teaching foundation subjects as they begin their careers

    Exploiting flavour preferences of common marmosets to increase palatability of a dry pellet diet

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    Although commercially available complete diets exist for common marmosets, the animals’ consumption of these diets (available in dry pellet form) is typically very low. Increasing consumption of the pellet diet could have positive consequences for the welfare of the marmosets as the pellets are designed specifically to meet their full nutritional requirements, and therefore an increase in intake should help to ensure that they take in an appropriate balance of nutrients. We carried out a series of studies targeted towards improving the palatability, and hence increasing the intake, of a complete dry pellet diet for marmosets. In Study 1 we attempted to determine which of a wide range of flavours appeared to be preferred by the marmosets. In Study 2 we tested the marmosets’ preferences for a smaller number of highly preferred flavours (as determined in Study 1) when actually added to the dry pellet diet in a series of paired preference tests. Finally, in Study 3 we tested whether adding the most highly preferred flavours (as determined in Study 2) to the dry pellet diet would in fact increase consumption of these pellets in comparison with unflavoured pellets. Despite finding strong and consistent preferences for particular flavours amongst the marmosets, we found that adding these to the pellets did not significantly increase consumption. Reasons for this are discussed, along with other potential modifications which might prove more successful in increasing consumption of pellet diets for marmosets

    Student perceptions of learning to teach the foundation subjects : How do pre-service teachers in England perceive the curriculum subjects in primary schools – and are foundations secure?

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    Our study examined the development of student expertise in teaching the primary foundation subjects. In the English primary national curriculum these include, art, design technology, history, geography, art, physical education, music, modern foreign languages and computing. The perceived marginalisation of foundation subjects is an ongoing concern across the sector, particularly for the arts and humanities. Since September 2019, English schools have been working to a new Ofsted inspection framework, which requires considering their curriculum in terms of both breadth and depth. It seemed timely to explore how Initial Teacher Education (ITE), in collaboration with the schools that support primary ITE students on teaching practice, can better facilitate opportunities for students in the foundation subjects. Whilst acknowledging that there are many routes into teaching, our research focussed upon a university-based training route. We explored the ITE student voice in order to understand the opportunities presented in schools and at university to teach and learn about foundation subjects. Data came from a final year cohort of 126 ITE students on a three-year undergraduate BA Primary Education with qualified teacher status. ITE student perceptions provide a starting point to reflect on these issues and present a challenge for how we respond to their voice

    The Panchromatic Hubble Andromeda Treasury I: Bright UV Stars in the Bulge of M31

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    As part of the Panchromatic Hubble Andromeda Treasury (PHAT) multi-cycle program, we observed a 12' \times 6.5' area of the bulge of M31 with the WFC3/UVIS filters F275W and F336W. From these data we have assembled a sample of \sim4000 UV-bright, old stars, vastly larger than previously available. We use updated Padova stellar evolutionary tracks to classify these hot stars into three classes: Post-AGB stars (P-AGB), Post-Early AGB (PE-AGB) stars and AGB-manqu\'e stars. P-AGB stars are the end result of the asymptotic giant branch (AGB) phase and are expected in a wide range of stellar populations, whereas PE-AGB and AGB-manqu\'e (together referred to as the hot post-horizontal branch; HP-HB) stars are the result of insufficient envelope masses to allow a full AGB phase, and are expected to be particularly prominent at high helium or {\alpha} abundances when the mass loss on the RGB is high. Our data support previous claims that most UV-bright sources in the bulge are likely hot (extreme) horizontal branch stars (EHB) and their progeny. We construct the first radial profiles of these stellar populations, and show that they are highly centrally concentrated, even more so than the integrated UV or optical light. However, we find that this UV-bright population does not dominate the total UV luminosity at any radius, as we are detecting only the progeny of the EHB stars that are the likely source of the UVX. We calculate that only a few percent of MS stars in the central bulge can have gone through the HP-HB phase and that this percentage decreases strongly with distance from the center. We also find that the surface density of hot UV-bright stars has the same radial variation as that of low-mass X-ray binaries. We discuss age, metallicity, and abundance variations as possible explanations for the observed radial variation in the UV-bright population.Comment: Accepted for publication in Ap

    Concert recording 2013-02-01

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    [Track 01]. Soon ah\u27 will be done / arranged by William Dawson -- [Track 02]. Twenty-four negro melodies, op. 59. Wade in the water / Samuel Coleridge-Taylor -- [Track 03]. Multiple voices of an expanding distance / Jeffrey Mumford -- [Track 04]. On music. Invitation ; The final prelude / Shawn E. Okpcbholo -- [Track 05]. Psalm for the living / William Grant Still -- [Track 06]. Warm valley / Edward K. Duke Ellington -- [Track 07]. Betelehemu / arranged by Wendell Whalum
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